Bagani is the story of five normal individuals, namely Lakas, Ganda, Lakam, Dumakulem and Mayari, all belonging to the land called Sansinukob. Each one of the five individuals belongs to one of the five different regions that make up Sansinukob. Lakas who hails from the desert region of formidable warriors, Ganda coming from the farming region of land natives, Lakam born from the lush and rich trade region, Dumakulem comes from the strong hunters of the forest region and Mayari hailing from the coastlines of the aquatic region.
Each of the five has a particular skill that makes them a cut above the rest within the tribes they belong to. But apart from their great skill, it is the goodness of their hearts and willingness to sacrifice themselves for their people that made them worthy of the great weapons of power that their god Apo have bestowed on them, weapons they will need to fight off the monsters that the evil god Sarimaw has unleashed upon Sansinukob in his bid to conquer the land and the people living in it.
In their journey, they will find out how love can both be poison and cure that heals the heart and ultimately conquer the evils that lie among and within themselves.